계산유전체학, 생명정보학, NGS 분석기법 및 알고리즘 개발, 체성 돌연변이 분석, 단일 세포 유전체학
학력
2009-2014: 박사, KAIST 바이오및뇌공학과
2008-2009: 석사, KAIST 바이오및뇌공학과
2004-2008: 학사, KAIST 바이오및뇌공학과
약력/경력
2021-현재: 성균관대학교 생명과학과 조교수
2017-2021: 보스턴 아동 병원 / 하버드대학교 의과대학 박사후 연구원
2014-2018: 연세대학교 의과대학 박사후 연구원
학술지 논문
(2023)
CanISO: a database of genomic and transcriptomic variations in domestic dog (Canis lupus familiaris).
BMC GENOMICS.
24,
1
(2022)
Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders.
NATURE COMMUNICATIONS.
13,
1
(2022)
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.
NATURE GENETICS.
54,
10
(2022)
Somatic genomic changes in single Alzheimer’s disease neurons.
NATURE.
604,
7907
(2022)
Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain.
CANCER DISCOVERY.
12,
1
(2022)
Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity.
Nature Aging.
2,
8